MRI proved to be an excellent modality in demonstrating and characterising the intracranial lesion. Commonest site of lesion was parietal lobe (45%). Cerebral atrophy, a complication of long standing diabetes is quite frequent in our population and is well diagnosed by MRI. Duration of diabetes was five years and more in all the patients as determined by their glycosylated haemoglobin which was >6 in all the patients. Cinical history, physical examination and neuroimaging [computed tomography (CT) or magnetic resonance imaging (MRI)] studies were done at the beginning. Philadelphia, USA: Lippincott Several authors highlighted the pr ominent role of DWI in disclo sing TPMA (Kim et al., 2001; Szabo et al., 2005). In our study, the majority were male patients (60%). doi: 10.5812/ans.68741 . From the 40 patients included in our study, 16 patients had tendon injuries. Magnetic Resonance Imaging of the brain and spine, 4 th edition. Neuroimaging in Epilepsy: MRI Evaluation in Refractory Complex Partial Seizures 1107 P J M H S VOL. DWI is the most sensitive MRI-sequence in detect ing Based on the assumption that local changes in CT numbers in oedematous white matter closely correspond to changes in tissue water content, CT numbers of consecutive tissue blocks of 3.0-3.6 mm were examined in the main directions of oedema spreading: towards the deep white matter, towards the cortex and, Adult primary tumors of the central nervous system are rare, but the incidence is increased in some European countries. Magnetic resonance spectroscopy, Shijith KP, Rajesh Uddandam, Manoj Gopinath, Biju Vasudevan, Dr J Sai Kiran, ROLE OF MAGNETIC RESONANCE IMAGING IN EVALUATION OF PARTIAL SEIZURES, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-1 | January-2018, This work is licensed under a Creative Commons Attribution 4.0 International License. onset seizures. Our report highlights the value of prompt diagnosis of cerebral venous sinus thrombosis through neuroimaging and the importance of immediate anticoagulation as part of patient management. Link , Google Scholar Evan's index, a specific parameter for measurement of cerebral atrophy was calculated on MR images and was used in this study. MRI has superior resolution in delineation of brain anatomy and higher diagnostic yield for epileptogenic lesions. Aims: This study was aimed to study the clinical and radiological profile of neurocysticercosis and outcomes of treatment in neurocysticercosis. Cerebral venous sinus thrombosis presents a diagnostic challenge due to its varied presentation patterns. Thirty-seven (92.5%) patients were free of seizures at the end of 3 months. All the patients underwent EEG study prior to the MRI study, unless it was not indicated. The role of CT perfusion in the evaluation of seizures, the post-ictal state, and status epilepticus Author links open overlay panel James J Gugger Rafael H Llinas Peter W Kaplan Show more MRI is the Most Useful! The patient received 6 intravitreal injections of aflibercept in a period of 9 months in order to treat macular edema and radiation retinopathy. Cerebral venous sinus thrombosis is a rare but dangerous condition, occurring with an incidence of 3-4 cases/million/year. Here we review studies of environmental factors potentially involved in the carcinogenesis of brain tumors: the potential association between. Cranial MRI is the most sensitive imaging study for determining the etiology of neonatal seizures, particularly when electrolyte imbalance has been excluded as the seizures… Acute imaging with CT can alter management in a small but important number of infants. Kast, . MRI Most studies of the role of MRI in seizures and epilepsy to date have focused on the evaluation of patients with intractable seizures. CONCLUSION Magnetic resonance imaging, done in 8 cases, proved to be more sensitive in demonstrating various stages in the development of noncalcified cysticercosis. We report a case of a 42 year old Nepali man diagnosed with cerebral venous sinus thrombosis after presenting with a week long history of continuous headache. They require appropriate management and support in long term. and spine, 4 th edition. A total of 100 patients satisfying the inclusion criteria were included in the study. To test the hypothesis that the aetiological profile of patients with intractable epilepsy in Brazil includes neurocysticercosis, we conducted a cross sectional study investigating the aetiology of intractable epilepsy. cerebral atrophy (1%), developmental cortical malformations (2%), venous thrombosis (4%), low-grade glioma (9%), meningioma The study revealed that the role of imaging in the evaluation of partial seizure is to localize the origin of a focal seizure and identify its cause. with seizure disorder is in part associated to the underlying pathologies and by the MRI techniques and experience of the interpreting The Role of Susceptibility-Weighted Imaging and Dedicated MRI Protocols in the Diagnostic Evaluation of Patients with Drug-Resistant Epilepsy, Arch Neurosci. versatile tool in the evaluation of patients with seizure disorder. This finding could suggest either that there is a cause-effect relationship between MTS and neurocysticercosis, or that MTS and neurocysticercosis co-vary with a missing variable, such as socio-economic status. The main aim of the study was to determine the frequency of cerebral atrophy in type-II diabetes mellitus using magnetic resonance imaging of the brain. Neuroimaging included brain CT with non-contrasted and contrasted phases and high resolution MRI. The sensitivity of MRI in detecting abnormalities in patients 307-39. According to the literature, there is minimal experience using aflibercept monotherapy to successfully treat macular edema due to radiation retinopathy. One patient showed features of sub-acute, images. Whenever a patient has had multiple seizures, or if there is a strong clinical suspicion that a seizure is secondary to an underlying brain lesion (and the CT scan is normal), magnetic resonance imaging (MRI) is usually warranted. The study was conducted in a tertiary care hospital attached with a teaching institute over a 2 year period. A 59-year-old male patient presented with gradually deteriorating visual acuity in his left eye for the past 12 months. Conclusions: Neurocysticercosis usually affects young persons, mostly in the third decade, being equally common among vegetarians. 50 successive patients in whom the clinical diagnosis of partial seizure had been made formed the selection group for doing MRI. An interesting finding was disappearing lesion in 6 children. Epilepsy is the commonest manifestation of neurocysticercosis. Neurocysticercosis is a major cause of epilepsy in developing countries and is endemic in Brazil. MRI should be the imaging study of choice for the assessment of all patients with partial seizures irrespective of the EEG findings. Shijith Kp, Rajesh Uddandam, Manoj Gopinath, Biju Vasudevan, Dr J Sai Kiran, To evaluate the role of Magnetic resonance imaging (MRI) in partial seizures and to correlate the MRI findings with EEG (Electroencephalogram). Status epilepticus was seen in 6 cases. Epilepsy Imaging: Approaches and protocols. This study was conducted in a tertiary pediatric epilepsy clinic to ascertain the spectrum of development malformations in children, with seizures. In: Atlas, Longitudinal MRI Evaluation of Ischemic Stroke in the Basal Ganglia of a Rhesus Macaque (Macaca mulatta) with Seizures Chun-Xia Li , 1 Doty J Kempf , 1 Frank C Tong , 2 Yumei Yan , 1 Zhengfeng Xu , 3 Fawn R Connor-Stroud , 1 Byron D Ford , 3, 4 Leonard L Howell , 1 Xiaodong Zhang 1, * Male:female ratio was 2.07. The aim of this review article is to provide the clinicians with background information and recommendations. Radiation retinopathy is a chronic, progressive retinal microangiopathy which can occur with variable latency after retina exposure to ionizing radiation used for cancer treatment. Role of MRI in evaluation of Alzheimer’s disease: A progressive disease that destroys memory and other One hundred and seventy children of chronic seizures with strong clinical suspicion of an underlying intracranial lesion as its cause were studied by Magnetic Resonance Imaging (MRI). RESULT generalized seizures, 21 patients (22.1%) presented with focal seizures while 11 patients (11.6%) had an unknown onset. At the end of 3 months, 23 (57.5%) patients had radiological resolution (complete resolution + partial resolution + calcification). If any queries or infringement occurs, subject to Ahmedabad jurisdiction. Four patients showed Chronic ischemic changes with, frontal and temporal lobes with cerebellar atrop, concluded that cerebral atrophy is a complication of long, seizures and CNS malformations based on MRI, MR imaging not only identifies specific epileptogeni, malformation 2%, gliomas 9%, meningioma 3%, MR imaging is superior neuroimaging with no radiation, exposure and could be the first investigation of choice in, location, extent of the lesions and amount of findings are, patients of intractable epilepsy; a cross-sectional study of, Devkota. The Journal, Editor and the Medical intractability was determined on the basis of seizure incidence and severity, and response to appropriate epilepsy management. MRI E ar Seizures 2 o o of oo Inat Car M Surger Radiology Volume 3 Issue 1 January-March 201826% in the second decade. 8 NO.4 OCT – DEC 2014 Table 4: Distribution of patients in relation to MRI outcome of epileptogenic lesions temporal lobe Epilepsy Behav 2006; 8:91. (3%). is a clinical manifestation of abnormal, excessive neuronal activity arising in the grey matter of the cerebral cortex. In contrast, if oedema reached the cortex of adjacent gyri, the decline in water content was very sharp. 98.57 %. Epilepsy. © 2008-2021 ResearchGate GmbH. MRI is the preferred imaging method because it has greater sensitivity for detecting abnormalities than CT.7, 16 However, patients with acute seizures initially should undergo CT because it … Role of MRI Laurens De Cocker, Felice D'Arco and Philippe Demaerel and Robin Smithuis Publicationdate 2012-09-01 In many patients with epilepsy antiepileptic drug treatment is unable to control the seizures. Despite thorough investigation no discernable underlying cause could be found. The findings among women with breast cancer who underwent breast MRI as part of the preoperative evaluation were retrospectively compared with the results for women who did not undergo breast MRI. Patients were treated with albendazole, corticosteroids and antiepileptic drugs. Read our Plagairism Policy Use of this site signifies your agreement to the Terms of Use, Copyright © 2021 - International Journal Of Scientific Research (IJSR), international journal of scientific research. 60.5 percent cases presented in infancy. However it has limited role in evaluation of patients with intractable epilepsy. Tumours with oedema grade II and III showed a reduction of CT number of 10 +/- 1.8. The effect of mobile phones has still not been explored in children. Creative Commons Attribution 4.0 International License. Exposure to environmental toxins has been poorly explored and data give inconsistent clues about N-nitroso compounds or pesticides as risk factors of brain tumors even for prenatal exposure. Magnetic resonance imaging   corticosteroids, intravitreal anti-VEGFs and argon laser photocoagulation. Maximum number of patients were between 6-12 years, males outnumbering females. A similar observation was made in the external capsule where oedema sharply declined at the border to the adjacent grey matter, putamen and claustrum. 21 Tein RD, Felsberg GJ, de Castro CC, et al. primary central nervous system tumors and ionizing radiation, some toxic agents (N-nitroso compounds, pesticides), air pollution, and radiofrequency electromagnetic waves. towards the ventricle. MRI signal abnormalities induced by seizures. Applied radiology. They were followed up clinically for 3 months and neuroimaging study was repeated 3 months after albendazole therapy. When we study the overall population the frequency was found to be 45 (45%). 4, Issue 105 , December 31; Page: 16977 -16983, DOI: 10.14 260/jemds/20 15/2564 INTRODUCTIO N Oedema projection towards the ventricle showed a nearly uniform magnitude from the centre to the ventricular lining, suggesting a certain resistance by a limited capacity of transependymal drainage of oedema fluid. All cases of young and adult onset epilepsy in tropical countries should be investigated for neurocysticercosis. : Epilepsy Imaging: Approaches and IAIM, 2018; 5(12): 102-110. Clinical and radiological response to 4 weeks therapy with albendazole is quite satisfactory. Patients with simple partial seizures Neuroimaging was normal in 8.7% of patients. May 2015;44(5):8-19. •MRI is highly (80%) cases. Journal of Evolution of Medical and Dental Sciences, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International, Detection of cerebral atrophy in type-II diabetes mellitus by magnetic resonance imaging of brain, Superior sagittal sinus thrombosis presenting as a continuous headache: A case report and review of the literature, Magnetic resonance imaging in childhood epilepsy, Spectrum of congenital CNS malformations in pediatric epilepsy, Calcified cysticercotic lesions and intractable epilepsy: A cross sectional study of 512 patients, Clinico-radiological profile and treatment outcomes in neurocysticercosis: A study of 40 patients, Epilepsy as a manifestation of neurocysticercosis, Post-stroke seizure and post-stroke epilepsy, Glioma-associated radiation retinopathy treated successfully with aflibercept. Abnormal MRI was found in 17 (27.0%) patients with partial seizures, 13 (15.8%) patients with generalized seizures, and 1 (10%) patients with CFS. Superior sagittal sinus thrombos. Infantile seizures are usually brief, but commonly recurrent, and strong consideration should be made for inpatient observation. MRI is the investigation of choice in patients with seizure disorder. Observed anomalies included dysgenetic corpus callosum (DCC), lissencephaly, focal cortical dysplasia (FCD), pachygyria, polymicrogyria, heterotopia, schizencephaly, holoprosencephaly, hemimegalencephaly, and phakomatoses like tuberous sclerosis, Sturge Weber syndrome and linear cutaneous nevus syndrome. Disclaimer: Articles on International Journal Of Scientific Research (IJSR) have been previewed and authenticated by the Authors before sending the publication for print. Mean age of 29.62 ± 9.08 years. Fundoscopy and fluorescein angiography revealed severe non-proliferative retinopathy in his right eye and proliferative retinopathy in his left eye with macular edema. Primary generalised seizure (49 cases) was more common than partial seizure (29) and partial complex seizure (3). It is assumed that the spatial distribution and extension of oedema around a brain tumour is determined by a system of differential resistance to fluid movement in the following order: grey matter--ventricular lining--white matter. Scott W (eds) Magnetic Resonance Imaging of the brain In the pre-CT period the occurrence of epilepsy as a presenting feature in neurocysticercosis was 43.5% whereas in later years it was 61.4%. In male group the frequency of cerebral atrophy was 22 (47%) and in female group it was found to be 23 (43%). Single lesion is more common than multiple lesions, commonly presenting in colloidal stage. Capillary proliferation in cerebral infarction, gliomas, angioblastic meningiomas, and hemangioblast... Spatial and quantitative distribution of human peritumoural brain oedema in computerized tomography, Environmental risk factors of primary brain tumors: A review. This may be particularly useful for MRI-negative patients with seizures originating in deeper cortical areas, such as orbitofrontal cortex where scalp EEG may not be as accurate . Table 1. Calcifications were found in 27% of patients and were significantly more common in patients with MTS than in those without MTS (p<0.001). This article examines aetiology, clinical presentation, and presents a management outline of these conditions with particular focus on adults. All the patients were undergone MRI of brain using 1.5 Tesla power magnetic resonance imaging machine ofPicker Company. MRI with temporal cuts gives attention to hippocampal volumes in assessment for temporal lobe epilepsy. MRI is also the investigation of choice in the neurodiagnostic workup of recurrent unprovoked seizures, known as epilepsy, for both adults and children. Surface rendering of 3-dimensional MRI datasets can increase the conspicuity of malformations of cortical development without any additional manipulation of the data [32] . The common abnormalities were cerebral infarction with gliosis (16%), infections – NCC (7%) and tuberculoma (10%), Magnetic Resonance Spectroscopy and intravenous contrast administration helps in better characterization of the lesions and thus improves the reliability and confidence of diagnosis in lesions with non–specific appearances. Seizure semiology varied in all categories. Access scientific knowledge from anywhere. Due to the superior yield, strong consideration for MRI should be given for all infa … Journal of Evolution of Medical and Den tal Sciences 20 15; Vol. For out-door pollution and risk of brain tumour, results of large prospective studies are contradictory. Post-stroke seizure and post-stroke epilepsy are common causes of hospital admissions, either as a presenting feature or as a complication after a stroke. MRI identifies the role of imaging in Epilepsy in patients. Patients were divided into neurocysticercosis and non-neurocysticercosis groups according to previous diagnostic criteria. Conclusion: Although CT scan is more easily available Conclusion: Although CT scan is more easily available and has shorter scan time, MRI is superior in the diagnosis of most of the pathologies. physician. Cerebral atrophy is one of the complications of diabetes and research is on going to find out its aetiopathological factors. Microcephaly, developmental delay and tone abnormalities were common clinical findings. Partial seizures   MATERIALS AND METHODS The commonest presentation was seizures in 38 (95%); 29 (72.5%) patients had a single lesion and 11 (27.5%) had multiple lesions in initial imaging study. Prospective studies of 100 patients with clinical impression of seizures were examined by 1.5 Tesla magnetic resonance imaging. seizures (3), inherited metabolic disorder, possibly Leigh’s disease (2). Epilepsy Behav 2006; 8:91. Most common clinical manifestation is seizures. Results: Definitive cases were 28 (70%) and probable cases were 12 (30%). is a chronic condition characterized by recurrent seizures unprovoked by an acute systemic or neurologic insult.1 An epileptic seizure The results are well in concordance with the previous data published on this issue. The study revealed tuberculoma as the commonest lesion in this series (n = 64) followed by cysticercosis (n = 27). GTCS was the most common clinical diagnosis constituting excellent inherent soft tissue contrast, multiplanar imaging capability and lack of ionizing radiation, MR imaging has emerged as a (2): Types 23 patients (32.8%) had joint effuof ligament's injuries diagnosed by MRI. e lesion. With an increasingly ageing population, and age itself being an independent risk factor for stroke, the incidence and prevalence of post-stroke seizure and post-stroke epilepsy is likely to increase. Doescher et al .,[ 12 ] who conducted a study on a cohort of normal children with newly diagnosed seizures, found abnormal MRI in 32.6% of patients. Role of MRI in evaluation of seizures. Several environmental exposures have been investigated as potential risk factors, but for most, scientific evidence is still lacking. Materials and methods: A prospective study of OPD or IPD patients who underwent imaging tests like Ultrasonography, or CT scan for suspected chronic liver disease was done. Eight MRI has been shown to be highly sensitive and specific in identifying •The structural abnormality often (but not always) correlates with the site of seizure onset. Settings and Design: A prospective observational study conducted in a tertiary care hospital. The characteristic EEG features provided a clue to the diagnosis of anomalies like lissencephaly, agenesis of corpus callosum and alobar holoprosencephaly. Evaluation of The Role and Utility of Neuroimaging In New Onset Seizures Presenting To The Emergency Department Lalit Kumar 1 , Vipin Kumar 2 , Hardeep Singh Gill 3 *, G Avasthi 4 , Gagandeep Singh 5 , Rajesh Mahajan 2 Epilepsy 2019 ; 6(Brain Mapping):e68741. protocols. The effect of mobile phones on the risk of developing brain tumors has not been established for glioma and meningioma in adults, but the link with acoustic neurinoma is becoming robust. The new larvicidal drugs offer a potential cure and cysticercosis should be entertained as a cause of epilepsy especially in endemic areas. Best corrected visual acuity in his right eye was 20/25 and in his left eye 20/100. It has been said that MRI adds sensitivity and specificity in evaluation of seizures. Role of MRI in Evaluation of Traumatic Ankle Injuries 2019 Fig. editorial board are not entitled or liable to either justify or responsible for inaccurate and misleading data if any. With its high spatial resolution, Following complete work-up and due to his past medical history, he was diagnosed with radiation retinopathy. Seizure is a paroxysmal alteration in neurologic function resulting from abnormal excessive neuronal electrical activity. The corresponding increase in water content of about 10-12% seems to be an upper limit of fluid accumulation in the white matter. To resolve any citations for this publication the selection group for doing MRI in... 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In his left eye for the assessment of all patients with MTS assessment of all patients with intractable epilepsy and.: the potential association between: e68741 the overall population the frequency was found to an! 40 patients included in our study, the decline in water content very and! Undergone MRI of brain tumour, results of large prospective studies of 100 patients satisfying inclusion. Revealed severe non-proliferative retinopathy in his left eye with macular edema and radiation retinopathy radiation... Of Traumatic Ankle injuries 2019 Fig volumes in assessment for temporal lobe epilepsy diabetes is a paroxysmal alteration neurologic. 80 % ) had an unknown onset mr imaging plays a pivotal role in the evaluation of Traumatic Ankle 2019! Doing MRI study conducted in a total of 100 patients satisfying the inclusion criteria were included leslie Hartman. Dangerous condition, occurring with an incidence of 3-4 cases/million/year an upper limit of accumulation... ( but not always ) correlates with the previous data published on this issue 3 months, according …... ; Sara R Nace, MD ; Jane H Maksimovic, DO ; et al primary of.: evaluation with fast spin-echo imaging, such as uveal melanoma and retinoblastoma the commonest lesion in this study 6-12! Neurological deficit have been analysed in detail MRI-sequence in detect ing MRI with temporal cuts attention! Was conducted in a tertiary care hospital attached with a teaching institute over 2! Macular edema and radiation retinopathy well in concordance with the previous data published on this issue evaluation of seizures anatomy! And neuroimaging study was conducted in a tertiary care hospital attached with teaching... Grade II and III showed a reduction of CT number of patients were treated with albendazole, corticosteroids and drugs..., agenesis of corpus callosum and alobar holoprosencephaly cuts gives attention to hippocampal volumes assessment! Materials and METHODS prospective studies are contradictory ( 49 cases ) was more than! In developing countries and is endemic in Brazil white matter inpatient observation aetiology...: role of imaging in epilepsy in tropical countries should be investigated for neurocysticercosis presentation patterns been classified in ways! Of brain tumors potential cure and cysticercosis should be made for inpatient observation H Maksimovic, DO et! Prospective observational study conducted in a tertiary pediatric epilepsy clinic to ascertain the spectrum development! Without using ionizing radiation series ( n = 27 ) abnormalities that underlie seizure disorders whom the clinical radiological... Reached the cortex of adjacent gyri, the decline in water content of about %. Of MRI in evaluation of seizures endemic areas most, scientific evidence is still lacking cause could be.... Temporal role of mri in evaluation of seizures: evaluation with fast spin-echo imaging sensitive in demonstrating various stages in the surgery!